PT-141

PT-141 (Bremelanotide) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH) that functions as a melanocortin receptor agonist. It has been studied in vitro for its activity on the MC3R and MC4R receptors, which are associated with neuroendocrine signaling, sexual function, and appetite regulation.

Unlike other melanocortin analogs (e.g., Melanotan II), PT-141 does not primarily affect pigmentation pathways and is instead researched for its unique role in modulating central nervous system activity related to arousal and reward mechanisms.

Refer to product certificate for exact content quantity. intended for advanced laboratory study.

Specifications:

• Unit Size: 10mg (lyophilized powder, single vial)
• Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: ~1025.2 Da
• Form: Crystalline lyophilized peptide
• Solubility: Soluble in sterile water or compatible aqueous buffers
• Storage: Store dry at 2°C–8°C in a sealed container.

Application Context:

PT-141 is studied in vitro for its potential roles in:

• Melanocortin receptor activation (MC3R/MC4R pathways)
• Central nervous system signaling and neuroendocrine research
• Arousal, libido, and reward system models
• Appetite and energy balance regulation

Intended Use:

This compound is intended strictly for in vitro laboratory research. It is not approved for human or animal administration and must not be used in food, dietary supplements, cosmetics, or pharmaceuticals.

Legal Disclaimer:

This product and related information have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, cure, or prevention of any disease. Use is restricted to qualified research professionals in certified laboratory environments.